Netherton综合征1例

Netherton's syndrome: one case report

报告1例Netherton综合征。患者女,43岁。患者自幼全身皮肤反复出现红斑、脱屑,严重时有渗出,伴有瘙痒。平时头发不易梳理、易断。幼时曾有哮喘史。皮损组织病理改变符合迂回线性鱼鳞病。毛发电镜检查示毛发呈竹节状,在竹节处有套叠。

A 43-year-old female had variable erythema and ichthyosiform eruptions over the entire body since her infancy. Her hairs were coarse and lusterless. She also had the history of asthma in her childhood. Histopathologic examination showed ichthyosis linearis circumflexa. Scanning electron microscopy indicated that hairs looked like 'bamboo node', swelling and invagination of the cuticle. The diagnosis was made as Netherton's syndrome.