广西银星竹鼠与人马尔尼菲青霉病关系的研究

Study on Relationship Between Rhizornys Pruinous and Human Penicilliosis Marneffei

目的 探讨动物与人马尔尼菲青霉病的流行病学关系。方法 收集 16只广西银星竹鼠进行真菌学研究。结果 从 15只竹鼠体内分离出与人类马尔尼菲青霉病的病原菌一致的马尔尼菲青霉菌 ,阳性率达 93 .2 %。结论 野生竹鼠自然携带马尔尼菲青霉菌 ,但无病态 ,其可能为该菌的贮存宿主。其分泌排泄物可通过呼吸道、消化道、皮肤等途径致人感染马尔尼菲青霉菌 。

Objective To explore the epidemiological relationship between animals and human penicillium marneffei (PM).Methods The mycologic investigation was conducted on 16 rhizornys pruinous,a species of bamboo rats trapped in various districts of Guangxi.Results Mycological cultivation demonstrated that 15 PM isolates were found in 16 rhizornys pruinous and the natural positive carrier rate was 93.2%.Conclusion Wildness rhizornys pruinous are PM natural carrier,but not morbidity.They may be PMs stockpile hosts.The secretion of them can infect human via respiratory canal,alimentary canal,and skin wound especially in low immunity.