门静脉高压性胃病

Portal hypertensive gastropathy

门静脉高压性胃病 (PHG)是一种内镜下胃粘膜呈特征性马赛克 (mosaic)样改变的疾病 ,与门静脉高压患者的胃肠道血液丢失有关 ,超过 6 5 %的肝硬化门静脉高压症患者会发展为PHG ,PHG也可发生于无肝硬化的门静脉高压症患者中。在门静脉高压症患者中 ,PHG的发生与肝病的严重程度及食管 胃底静脉曲张有关。但其发病机制目前还不清楚。PHG的诊断依靠内镜和组织学 ,治疗主要针对降低门静脉压力 ,应用β 受体阻滞药或分流术。

Portal hypertensive gastropathy (PHG), a term used to describe the endoscopic appearance of gastric mucosa with a characteristic mosaic-like pattern, is characterized entities that can be associated with gastrointestinal blood loss in patients with portal hypertension. More than 65% of patients with portal hypertension from cirrhosis will develop PHG,however,it could also occur in the setting of non-cirrhotic portal hypertension. In patients with portal hypertension, the incidence of PHG was associated with severity of liver disease and the presence of both oesophageal and gastric varices. The exact etiology of PHG is not clearly defined, the diagnosis of PHG depends on endoscopy and histology, therapy of PHG is directed at lowering portal pressure by β-blockers or shunt procedures.