中浆患者对侧眼的对比敏感度研究

Contrast Sensitivity Study in the Fellow Eyes of Patients with Central Serous Chorioretinopathy

对比敏感度(contrast sensitivity,CS)是反映视功能最敏感的指标之一。本研究用美国VCTS 6000型CS测试板对单眼中心性浆液性脉络膜视网膜病变(简称中浆)患者的对侧眼(20只)进行CS检查,同时设立按年龄配对的对照组。从对照组中获得一组正常值,在直角座标系上呈倒“U”字形曲线。随着年龄的增长,CS有所下降。有40％的患者其对侧眼出现轻度的中、高空间频率的CS下降。这些健眼在今后的随访中可能会发病。本实验首次显示了用CS对中浆进行亚临床诊断的可能性。

In clinical practice, it has been shown that the contrast sensitivity (CS) test is one of the most sensitive visual functional tests. In our experiment, we used a U.S.-made VCTS 60000 CS test plate to test the fellow eyes(20) of 20 cases with unilateral central serous chorioretinopathy (CSC), along with age-matched normal controls. From the control group, we obtained a group of bell-shaped normal CS curves which snowed some degree of decrease with age. 40% of the fellow eyes of the patient group showed a slight CS decrease at mid-high spatial frequencies, though other visual functional tests show no abnormality. These fellow eyes may be at risk for CSC. Our experiment, for the first time, showed the possibility of using the CS test as a diagnostic test for subclinical CSC.