湖北地区中老年人群血清胆固醇水平与生活方式的相关研究

Relationship between lifestyle and serum cholesterol in middle-old age men.

目的 探讨中老年健康人群血清总胆固醇 (TC)、高密度脂蛋白 胆固醇 (HDL C)、低密度脂蛋白 胆固醇 (LDL C)水平及与相关个体因素的关系。方法 横断面调查方法进行问卷调查、体格检查和血脂水平测定。结果 340例 4 5岁以上者 (男 183例、女 15 7例 )血清胆固醇水平均在正常范围 ;女性TC、HDL C及LDL C水平均显著高于男性 (P <0 .0 5 ) ;70～ 91岁组HDL C水平均显著高于其它年龄组。逐步回归分析显示 :显著影响TC水平的个体因素为年龄、性别 ,影响LDL C的因素为年龄、性别和体重指数 (BMI) ,影响HDL C水平的因素为年龄、饮酒、BMI。结论 超重和肥胖、经常大量饮酒是升高血胆固醇的重要因素。

Objective To study the relationship between lifestyle and serum total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C).Methods By using cross-sectional study, self-designed questionnaires were performed. Serum lipid levels were determined in 340 middle-old age men without any clinical appearance of cardiovascular diseases or lipid metabolism disorder.Results The levels of TC, HDL-C, LDL-C in women were significantly higher than in the men. The serum level of HDL-C in the people over 70 years (male or female) was higher than that of other age groups (P< 0.05). Stepwise regression analyses revealed that individual factors significantly influencing the TC were age and sex; those for LDL-C were BMI, age and sex; and those for HDL-C were BMI, alcohol intake and age.Conclusion Overweight and obesity are still main factors that affect serum cholesterol level in middle-old men. Both a fit MBI and good daily lifestyles are significance to regulate blood lipid levels.