脑白质稀疏症MRI与临床对照分析

A comparative analyze of MR imaging and clinical findings in leuko-araiosis

目的 探讨脑白质稀疏症的MRI表现与临床对照分析。方法 收集资料完整经MRI诊断为脑白质稀疏症者86例,对其MRI表现进行回顾分析,并与临床表现进行比较。结果 脑白质稀疏症在MRIT2加权像呈高信号,T1加权像呈等或低信号,病灶主要位于大脑皮层下白质区域,累及额叶(100%)、枕叶(84%)、顶叶(80%)、半卵圆中心(78%)及脑干(2%),常伴有不同程度脑室扩大、脑萎缩及多发脑梗死等,其临床主要表现为智能障碍、脑卒中反复、高血压、进行性痴呆等。结论 MRI是发现脑白质稀疏症的主要手段,对防治老年性痴呆有重要意义。

Objective To study the MRI findings of leuko-araiosis,and to compare the findings with the clinical data.Methods MRI findings of 86 patients,being diagnosed with a 0.2T MR unit,were retrospectively analyzed ,and compared with clinicul features.Results Leuko-araiosis lesions exhibited high signal intensity compared with brain on T 2 weighted image,while T 1 weighted image showed lower signal.The lesions of leuko-araionsis were mainly located at subcortical white matter,involving frontal lobes(100%),occipital(84%),parietal(80%),centrum semioval(78%) and brainstem(2%),together with varying degrees of dilatation of the lateral ventrides,atrophy of brain and multiple infarcts,etc.The clinical features included intellectual disturbance,apoplectic stroke,hypertension,dementia,etc.Conclusion MRI is very helpful indetecting leuko-araiosis and in preventing senile dementia.