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急性泛发性发疹性脓疱性皮病14例临床病理分析

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摘要 目的 了解急性泛发性发疹性脓疱性皮病(ACEP)的发病原因、临床病理特征及治疗情况。方法 回顾性分析14例AGEP患者的临床资料。结果 14例患者中2例有银屑病病史,男女发病之比为1:3,平均发病年龄31.3岁。7例患者发病前有明确的用药史,4例有病毒或细菌感染史,11例患者有发热及白细胞和嗜中性粒细胞增多。AGEP病程短暂且有自限性。组织病理学检查示表皮内或角质层下脓疱和真皮浅层水肿。去除诱发因素(药物和清除感染灶),给予中小剂量的糖皮质激素口服或注射,患者基本痊愈。结论 AGEP为一种较为少见的疾病,多由药物引起,临床及病理上具有特征性,去除诱发因素和及时应用糖皮质激素是治疗的关键。
出处 《临床皮肤科杂志》 CAS CSCD 北大核心 2003年第B12期44-47,共4页 Journal of Clinical Dermatology
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