息隐配伍米索前列醇用于稽留流产50例临床观察

Clinical observation of mifepristone and misoprostol used to cure 50 missed abortion patients

目的 针对传统方法处理稽留流产时出现的困难及并发症多的难点 ,探讨息隐配伍米索前列醇治疗稽留流产的效果及可行性。方法 对 10 0例被确诊为稽留流产 (missedabortion)的患者随机分为两组 ,应用息隐配伍米索前列醇与单独应用己烯雌酚进行对比观察。结果 息隐配伍米索前列醇治疗方法完全流产率4 0 % ,明显优于己烯雌酚治疗方法 (P <0 .0 1) ,清宫术及钳刮术前不需扩宫颈 ,阴道流血少 ,无人工流产综合反应发生 ,胃肠道反应轻微。结论 采用息隐配伍米索前列醇的方法治疗稽留流产效果好 ,安全可靠 ,己烯雌酚效果较差。

Objective: There are some difficulties and compl ic ations in dealing with missed abortion with traditional methods This article is to discuss the effect and possibility of using mifepristone and misoprotol to cu re missed abortion.Methods: One hundred missed abortion patients who had been diagnosed were divided into two groups at random. One group was cu red with mifepristone and misoprostol,the other group was cured with diethylsti lbestrol,the compare with the results.Results:The rate of comp lete abortion of one group who used miferpristone and misoprostol was 40%. Ob viously better than the other group who used diethylstilbestrol( P <0.0 1) and the former didn't need dilate cervix before Curettage and Forceps Curetta ge,Vaginal bleeding was small,no induced abortion reaction and only little sto mach reaction.Conclusions: Using mifepristone and misoprostol to cure missed abortion is better and more safe than that of using diethylstilbest rol.