针刺镇痛与血清中P物质含量变化关系的研究

The Research of Relationship Between Acupuncture Analgesia and the Content of Substance P in Serum

半个世纪前,Von Euler和Gaddum在猫的脑和小肠的提取液中发现一种强效的舒血管物质,他们将其命名为 P 物质(SP)。20年后有几个实验室相继证实 SP 的含量在脊髓背根高于脊髓腹根。基于这个发现 Lemb-

We determiuated the content of substance P ofserum in the patient suffering from pain syndromewith radioimmunoassay before and after acupunctureanalgesia.The results suggested that acupuncturemay obviously reduce the content of substance P inthe serum of the patients with pain syndrome andproved that acupuncture may reduce the release ofsubstance P(through some mechanisms)leading toproduce analgesic effects.Thereby,the change of thecontent of substance P in the serum may be used asthe appraisable target of acupuncture analgesia.