中西医结合治疗IgA肾病疗效观察

Study on Treatment of IgA Nephropathy by Integrated Traditional and Western Medicine

对经肾活检证实的45例IgA肾病患者,分为中西医结合治疗组西药对照组、进行对比观察疗效。结果:治疗组总有效率为86.36%,对照组总有效率为13.04%.两组比较有显著性差异(P<0.01)。显示中西医结合治疗组的疗效明显优于西药对照组。提示在辨证论治的基础上选用活血化瘀中药治疗,是治疗本病较为理想有效的方法。

45 cases of IgA nephropathy were confirmed by renal biopsy and were divided into 2 groups, the integrated traditional and western medicme (TCM-WM) therapeutic group and the western medicine (WM) therapeutic group. The WM group was treated by conventional western medicine (persantin, vitamin B co.), and the TCM-WM group was treated by the same western medicine plus differential symptomatic treatment with decoction of Chinese crude herbs. In this paper, most patients (30 cases)were present as deficiency of Yin(阴) of the Liver and Kidney type, and were treated by Qiju Dihuang pill(杞菊地黄丸) plus Erzhi pill(二至丸), All types in TCM-WM group were also used herbs of promoting blood circulation and remove blood stasis in almost every case. After 6 months of such treatment, the total effective rate of TCM-WM group and the WM group were 86.4% and 13.0% respectively. There was very significant difference (P<0.01) between them. The results showed that the curative effect of the TCM-WM group was much superior than WM alone for the treatment of IgA nephropathy.