从增龄对本虚标实证的影响探讨中医衰老机理

Effect of Aging on the Syndrome of Essential Debility and Evil Reality——An Exploration on Mechanism of Senility by Traditional Chinese Medicine

本文通过878例中老年人中医症候流行病学调查,结果表明随着年龄不断增长,机体各脏器虚损及气滞、血瘀痰浊等实证的患病率也不断增高呈显著正相关,进而提出中医衰老机理为多脏器虚损与痰浊、气滞、血瘀等实证相互作用,即本虚与标实证的相互作用,本虚导致标实,标实使本更虚,循环反复,造成全身性功能减退,以至衰竭。因此,作者认为在研制延缓衰老中医药制剂时,应把"补虚为主、泻实为辅"作为基本方向。

Effect of aging on essential debility and evil reality was explored by an epidemiological investigation of clinical syndrome with TCM in 878 cases of middle and old-aged patients, inquiring into their relation of senility with visceral weakness and stagnation of Qi((?)), blood stasis, and phlegm turbid. The results indicated that (1) several viscera, feeble and damaged, were the basis of senility, and the feeble kidney was the stress; (2) the syndrome of stagnation of Qi, blood stasis and phlegm turbid speeded up process of senility. The mechanism of feeble phenomena appeared in the middle-old aged patients is that with the rise of age in the patients observed there was interaction between the feeble visceral function and the syndrome of stagnation of Qi, blood stasis and phlegm turbid, that is, there was interaction between essential debility and evil reality. Essential debillity may lead to evil reality and the latter will worsen essential debility. Thus, on repeating themselves in alternate cycles, a systemic hypofunction will be formed up to exhaustion. Therefore, 'to nourish essential debility first and to purge evil reality second' should be considered as an essential direction of preparing antiaging drugs in TCM.