益气补肾冲剂治疗慢性肾功能不全的初步临床及实验研究

Preliminary Experimental and Clinical Study on Treatment of Chronic Renal Insufficiency by Granule of Yi-Qi Bu-Shen

本文报道运用中药益气补肾冲剂治疗慢性肾功能不全的临床及实验研究。初步证实该冲剂具有降低血尿素氮、肌酐浓度和提高内生肌酐清除率的作用,并能减少尿蛋白,改善血脂和贫血,对患有脾肾气阴两虚症状如腰疫痛、神疲、纳差、夜尿等均有疗效。

The effects of the granule of Yi-Qi Bu-Shen on the chronic renal insuficiency (CRI) was studied. 30 cases of CRI patients using the granule was compared with other 23 CRI patients by using Aldehyde-coating Oxidated Starch in same conditdons. The effective rate of these 2 groups were 53.3% and 42.9% respectively (P>0.05). According to laboratory observation, the granule had the ability to reduce BUN,Scr,Ch,TG and increase Ccr, Hb. The granule also could relieve symptom of Kidney-deficiency(肾虚). Animal experimental research suggested the granule had the function of reducing BUN, Scr and could improve pathological changes in rat kidneys. The conclusion were that the granule was effective on treating CRI and could postpone the progress of CRI.