冠心病中西医易患因素的743例临床流行病学调查

Clinical Epidemiological Study on Risk Factors of Coronary Heart Disease in 743 Subjects

本文通过743例福建省直机关干部临床流行病学调查,探讨了冠心病的中、西医易患因素。多元分析表明:高血压、糖尿病、总胆固醇、吸烟、超重、舒张压、皮质醇及中医衰老指数、气滞、血瘀、气虚、心虚为冠心病的主要易患因素。有关西医易患因素的结果与国内外目前的认识基本一致。此外,还筛选出了一批中医易患因素,且是西医易患因素所不能替代的。提示冠心病的发病既有西医易患因素,又有中医易患因素。因而宜采取中西医结合的方法对冠心病进行防治。

This paper sums up the clinical epidemiological investigation data on risk factors (RF) of coronary heart disease (CHD) among 743 office workers, with an average age of 61.0±8.0. The investigation involved factors relating to history physical examination, iochemistry, blood rheology and TCM Syndrome Differentiation. According to the results of the computerized single-factor correlation analysis, the incidence of CHD in RF exposed group was obviously higher than that of unexposed one. 65 RF such as hypertension, diabetes, hyperlipemia, smoking, body weight, HDL-C/TC, blood viscosity etc. were recorded. Using multivariate egressive analysis it revealed that hypertension, diabetes, total cholesterol, heavy cigarette smoking overweight, diastolic pressure,cortisol, TCM senile index, Blood Stasis Syndrome Qi Stagnation Syndrome, Qi Deficiency Syn-drome and Heart Deficiency Syndrome were the main RF. The result concerning RF of Western medicine (WM)was in conformity with that at home and abroad. In addition, some TCM-RF were selected which couldn' t be replaced by WM-RF. These indicate that there are TCM-RF and WM-RF in the development of CHD and it is better to adopt the method for preventing and treating CHD with combined TCM-WM. As to TCM-RF of CHD, the authors consider that there are both the factors of Deficiency and Excess, so preventing and treating CHD Should aim at reinforcing the Deficiency and reducing the Excess.