丹参对大白鼠冠状动脉结扎引起心肌缺血的预防作用

Effect of Salvia Miltiorrhiza on the Cardial Ischemia in Rats Induced by Ligation

给大白鼠腹腔注射丹参水提物(5g生药/kg),对于结扎冠状动脉引起的急性心肌缺血有明显的预防作用,给药组动物由于心肌缺血而提高的心电图"S-T"段大大低于对照组,左室心肌缺血面积显著缩小,动物的存活率也有所提高。

I. p. injection (5g crude drug/kg) of water exract of Salvia miltiorrhiza to S. D. rats can prevent the acute cardial ischemia induced by the ligation of the coronary artery The elevation of S-T segment in the electrocardiogram caused by the ischemia was greatly reduced in animals treated with Salvia miltiorrhiua compared with control group The ischemia area in the left ventricle was significantly reduced and survival rate of the rats increased.