中西医结合治疗小儿肾病综合征100例临床观察

Clinical Observation on Treatment of 100 Children with Infantile Nephrotic Syndrome by Integrated TCM-WM

采用中医辨证,并联合西药治疗小儿肾病综合征100例与西医组50例对比治疗,结果中西组总有效率达100%,完全缓解率86%,明显高于西医组(P<0.005和0.01)。中西组对肾炎性肾病疗效优于西医组(P<0.05)。从提高血浆总蛋白、白蛋白和降低胆固醇来看,中西组明显好于西医组(P<0.001)。在提高淋转率、E花环方面,中西组优于西医组(P<0.01)。温补脾肾中药在提高血浆皮质醇含量方面明显优于西医组(P<0.001)。

For ten years (1979-1989), 150 cases of infantile nephrotic syndrome were treated by integrated TCM and Western medicine (WM). The WM group (50 cases) was treated by conventional WM drugs (prednison, CLB, etc) and the TCM-WM group (100 cases) was treated by the above-mentioned WM plus treatment according to Syndrome Differentiation with decoction of Chinese medicinal herbs.Wulin San (五苓散), Zhenwu Tang (真武汤) and Zhibai Dihuang Tang (知柏地黄汤) were selected in treating Spleen-Qi Deficiency distressed by Dampness, both Spleen-Kidncy Yang Deficiency and both Liver-Kidney Yin Deficiency Syndrome respectively. The total effective rate was 100%, and the efficacy of TCM-WM group was higher than that of WM group (P<0.005). The efficacy of TCM-WM treatment of nephritic nephropathy was far better than that of simple nephropathy (P<0.05). Also the efficacy of TCM-WM was superior in raising plasma albumin and reducing blood cholesterol than that of WM (P<0.001). The cellular immunity function and plasma cortisol of TCM-WM group were significantly improved than that of WM, P<0.01 and 0.001 respectively. The result showed that the curative effect of the TCM-WM group in. treating nephrotic syndrome was much better than that of WM alone.