硝酸咪康唑栓剂400mg联合霜剂治疗外阴阴道念珠菌病的疗效观察

A Three Day study with Miconazole Ovula 400mg and Cream in Vulvovaginal Candidiasis

目的 :观察并评价阴道应用硝酸咪康唑 4 0 0mg联合外阴使用硝酸咪康唑霜的 3日疗法对外阴阴道念珠菌病 (VVC)患者的疗效。方法 :采用多中心大样本开放性研究 ,对 4 5 71例VVC患者阴道应用硝酸咪康唑 4 0 0mg并联合外阴使用硝酸咪康唑霜 ,共 3日 ,观察疗效及副反应。结果 :①第 1次复诊时的治愈率为 93.35 %、第 2次复诊时可达97.4 8%。②患者满意和较满意者在第 1次复诊可达 86 .5 % ,第 2次复诊高达 91.0 %。③无严重不良反应发生 ,仅 0 .96 %的患者出现局部的刺激症状。结论 :阴道应用硝酸咪康唑 4 0 0mg栓剂及外阴应用硝酸咪康唑霜治疗VVC有效。

Objective: To study the curative rate of combining Miconazole Ovula 400mg and Cream in vulvovaginal candidiasis (VVC). Methods: 4571 outpatients with VVC had been treated with Miconazole Ovula 400mg inside vagina and Miconazole Cream on vulva for 3 days. The curative effect and side effect were observed. Results: ①The cure rates were 93.35% in the first follow-up and up to 97.48% in the second follow-up. ② The satisfactory rate of patients were 86.5% in the first follow-up and up to 91.0% in the second follow-up. ③There had no severe side effects during the treatment of Miconazole . Conclusions: The treatment of Micnazole Ovula 400mg and Cream in VVC is effective, safety, and good compliance.