治疗方案对原发性肝癌预后影响的Cox回归分析

Prognostic Impact of Treatmnt Modalities on Liver Cancer Patients,An Analysis by Cox Regression Technic

本文应用Cox回归方法研究了影响肝癌患者预后的诸因素。性别,发病年龄,肝癌发生部位等因素对生存期无明显影响。化疗、肝叶切除、分枝动脉结扎和栓塞、固有动脉结扎均可延长生存期。通过Cox回归方法研究诸治疗方案的相互作用,结果表明在14种不同治疗方案组合中有8种有效。其中非插管化疗+肝叶切除的疗效较好,优于其它7种方案,两比较P值均小于0.05。

Prognostic factors of primary liver cancer were analyzed by the method of Cox regression.Sex,age and site of the lesion were not found to be of prognostic value.Patients treated with infusion chemotherapy via hepatic artery,systemic chemotherapy,resection of the tumor,hepatic artery ligation and embolization had better prognosis.Survival time was prolonged in patients treated by 8 out of 14 combined treatment approaches.Patients treated by infusion chemotherapy plus resection showed better results than the others (P value<O.05)