期刊文献+

肝细胞生长因子及其受体与肝细胞癌 被引量:1

Hepatocyte growth factor and its receptor in hepatocellular carcinoma
下载PDF
导出
摘要 肝细胞生长因子 (HGF)是正常肝细胞增生的强促有丝分裂原。近年研究发现 ,HGF同样影响肝细胞癌的生物学行为 ,其受体 (c Met原癌基因编码蛋白 )也与原发性肝癌关系密切 。
出处 《国外医学(肿瘤学分册)》 2004年第4期279-282,共4页 Foreign Medical Sciences (Cancer Section)
  • 相关文献

参考文献1

二级参考文献51

  • 1Ueki T;Kaneda Y;Tsutsui H.Hepatocyte growth factor gene therapy of liver cirrhosis in rats[J],1999(2).
  • 2Cao B;Su Y;Oskarsson M;Zhao P,Kort EJ,Fisher RJ,Wan LM,Vande Woude GF.Neutralizing monoclonal antibodies to hepatocyte growth factor/scatter factor (HGF/SF) display antitumor action in animal models[J],2001(98).
  • 3Atabey N;Gao Y;Yao ZJ;Breckenridge D,Soon L,Soriano JV,Burke TR,Bottaro DP.Potent blockade of hepatocyte growth factor-stimulated cell motility, matrix invasion and branching morphogenesis by antagonists of Grb2 Src homology 2 domain interaction[J],2001(17).
  • 4Furge KA;Zhang YW;Vande Woude GF.Met receptor tyrosine kinase:enhanced signaling to the adapter proteins[J],2000(49).
  • 5Shaharabany M;Abramovitch R;Kushnir T;Tsarfaty G,Ravid Megido M,HorevJ,Ron R,Itzchak Y,and Tsarfaty I.In vivo molecular imaging of met tyrosine kinase growth factor rqceptor activity in normal organs and breast tumors,2001.
  • 6Boccaccio C;Ando M;Tamagnone L;Bardelli L,Michieli P,Battistini C,andComoglio PM.Induction of epithelial tubules by growth factor HGF depends on the STAT pathway[J],1998.
  • 7Gual P;Giordano S;Anguissila S;Parker PJ,Comoglio PM.Gabl phosphorylation: a novel mechanism for negative regulation of HGF receptor signaling[J],2001(2).
  • 8Sachs M;Brohmann H;Zechner D;Muller T,Hulsken J,Walther I,Schaeper U,Birchmeier C,Birchmeier W.Essential Role of Gabl for signaling by the c- Met in vivo[J],2000.
  • 9Moriuchi A;Hirono S;Ido A;Ochiai T,Nakama T,Uto H,Hori T,Hayashi K,Tsubouchi H.Additive and inhibitory effects of simultaneous treatment with growth factors on DNA synthesis through MAPK and G1 cyclins in rat hepatocytes[J],2001.
  • 10Karihaloo A;O′ Rourke DA;Nickel C;Spokes K,Canlley LG.Differential MAPK pathways utilized for HGF- and FGF-dependent renal epithelial morphogenesis[J],2001.

共引文献23

同被引文献18

  • 1辛华,郑雅娟,韩振国,房德忠.肝细胞生长因子对癌细胞向血管内游走的影响[J].吉林大学学报(医学版),2004,30(4):589-590. 被引量:3
  • 2Shin S, Sung BJ, Cho YS, et al. An anti-apoptotic protein human survivin is a direct inhibitor of caspase-3 and-7 [J]. Biochemistry,2001,40:1117-1123.
  • 3Li F, Ambrosini G, Chu EY, et al. Control of apoptosis and mitotic spindle checkpoint by survivin [J]. Nature,1998,396:580-584.
  • 4Altieri DC. The molecular basis and potential role of survivin in cancer diagnosis and therapy [J]. Trends Mol Med,2001,7:542-547.
  • 5Ito T, Shiraki K, Sugimoto K, et al. Survivin promotes cell proliferation in human hepatocellular carcinoma [J]. Hepatology,2000,31(5):1080-1085.
  • 6Sohn J, Khaoustov VI, Xie Q, et al. The effect of ursodeoxycholic acid on the survivin in thapsigargin-induced apoptosis [J]. Cancer Lett,2003,191(1):83-92.
  • 7Marusawa H, Matsuzawa S, Welsh K, et al. HBXIP functions as a cofactor of survivin in apoptosis suppression [J]. EMBO J,2003,22(11):2729-2740.
  • 8Shigeno M, Nakao K, Ichikawa T, et al. Interferon-alpha sensitizes human hepatoma cells to TRAIL-induced apoptosis through DR5 upregulation and NF-kappa B inactivation [J]. Oncogene,2003,22(11):1653-1662.
  • 9Ikeguchi M, Ueda T, Sakatani T, et al. Expression of survivin messenger RNA correlates with poor prognosis in patients with hepatocellular carcinoma [J]. Diagn Mol Pathol,2002,11(1):33-40.
  • 10Ikeguchi M, Hirooka Y, Kaibara N. Quantitative analysis of apoptosis-related gene expression in hepatocellular carcinoma [J]. Cancer,2002,95(9):1938-1945.

引证文献1

二级引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部