细胞粘附与耐药在血液系统肿瘤中的研究
The study of cell adhesion and drug resistance in hematopoietic malignancies
摘要
细胞粘附介导的耐药 (CAM DR)使肿瘤细胞初始暴露于细胞毒药物时在肿瘤微环境中受到庇护 ,最终导致肿瘤细胞残留和经典耐药发生。造血微环境中的细胞外基质、骨髓基质细胞和细胞因子均参与血液系统肿瘤CAM DR的发生 ,对疾病复发和耐药起重要作用。
出处
《国外医学(肿瘤学分册)》
CAS
2004年第4期309-312,共4页
Foreign Medical Sciences (Cancer Section)
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