外耳道腺样囊性癌(附7例临床分析)

Adenoid cystic carcinoma of external auditory canal:a report of 7 cases

目的 :探讨外耳道腺样囊性癌的临床病理特点及提高诊治水平的手段。方法 :回顾性分析 7例外耳道腺样囊性癌患者的临床表现、治疗及随访结果。结果 :本组病例从出现症状到确诊时间平均为 5 .7年 ,全部行手术治疗。随访时间 2年 8个月～ 9年 11个月 ,5例复发 ,其中 2例死亡。结论 :外耳道腺样囊性癌不易及时确诊 ,肿瘤生长缓慢 ,易复发 ;可侵犯至腮腺甚至颅内 ,易发生肺转移。应行扩大手术治疗 ,术后辅以放疗。长期随访提示该病预后不佳。

Objective:To detect the clinical and pathological features of the adenoid cystic carcinoma of external auditory canal, and to improve its diagnosis and treatment level.Method:A retrospective analysis was performed on 7 patients with ACCEAC by their clinical manifestation, the therapy and follow-up results as well as the combination with the review of related literature.Result:The period from the appearance of primary symptoms to definite diagnosis averaged 5.7 years. All patients were treated by surgical excision and followed up from 2 years 8 months to 9 years 11 months. Five of them were recurrent after operation, 2 of which died.Conclusion:Adenoid cystic carcinoma of external auditory canal, which is rarely seen in clinic, is not easy to exact diagnosis in early stage. It progresses slowly and tends to invade parotid and even intracranial cavity. It also has the tendency of recurrence and pulmonary metastasis. So, it's necessary to do both aggressive surgery and postoperative irradiation. The long term follow-up indicates that the tumor has a poor prognosis.