1-溴-3-乙氧基丙烷的合成

Synthesis of 1-Bromo-3-ethoxypropane

3-氯丙烯与乙醇钠在乙醇中回流制得3-乙氧基丙烯,继而在过氧苯甲酰存在下,与溴化氢经反马氏加成制得1-溴-3-乙氧基丙烷,总收率89.2%。

Bromo-3-ethoxypropane was synthesized with an overall yield of 89.2% from 3-chloropropene bycondensation with sodium ethylate in ethanol to form 3-ethoxypropene followed by anti-Markovnikov addition with HBr inthe presence of benzoyl peroxide.