摘要
目的 :设计合成一系列新的取代苯甲醛缩二胺类双席夫碱 ,通过抗菌活性测试寻找具有抗菌活性药物。方法 :以取代苯甲醛与二胺类经缩合反应 ,合成席夫碱 ,并进行体外抑菌活性筛选。结果 :合成了 8种席夫碱 ,其结构经元素分析、IR和 H1 NMR确证。结论
Objective: A series of novel substituted benzaldehyde diamines Schiff bases were synthesized for screening antibacterical agents. Methods: The Schiff bases were prepared by the condensation reaction of substituted benzaldehyde with diamines. Their antibacterial activities were tested. Results: Eight novel Schiff bases were synthesized and their structures were identified by elementary analysis, IR spectra and H 1NMR. Conclusion: The synthetic Schiff bases have displayed significant antibacterical activities.
出处
《内蒙古医学院学报》
2004年第1期7-9,共3页
Acta Academiae Medicinae Neimongol
基金
内蒙古自治区自然科学基金资助项目 ( No.980 5 3 )
关键词
取代苯甲醛
席夫碱
二胺类
抗菌活性
substituted benzaldehyde
Schiff bases
diamines
antibacterial activities
