妊娠期糖耐量降低对新生儿的影响

Effect of Gestational Impaired Glucose Tolerance on the Newborns

目的 探讨妊娠期糖耐量降低 (GIGT)对新生儿的影响。方法 对GIGT孕妇 5 2例 (GIGT组 )、正常孕妇 4 0例 (对照组 )的新生儿进行比较。结果 GIGT组巨大儿发生率明显高于对照组 (2 1.2 %vs 5 .0 % ) ,(P <0 .0 5 ) ,生后 2h血糖均值低于对照组 [(1.5 2± 0 .6 6 )mmol/Lvs (2 .5 8± 0 .5 7)mmol/L](P <0 .0 1) ,低血糖、高胆红素血症、红细胞增多症等并发症发病率高于对照组 ,但差异无显著性。结论 GIGT对新生儿的预后有一定影响 。

Objective To study the effect of gestational impaired glucose tolerance (GIGT) on the newborns. Methods Fifty two newborns born to women with GIGT (GIGT group) and 40 newborns (gestational age matched) born to normal women (control group) were recruited in this study. Results The incidence of macrosomia in the GIGT group was obviously higher than that of the control group ( 21.2% vs 5.0% ; P< 0.05 ). The blood glucose level in the GIGT group at 2 h of life was significantly lower than that of the control group [( 1.52 ± 0.66 ) mmol/L vs ( 2.58 ± 0.57 ) mmol/L; P< 0.01 ]. Although the incidences of hypoglycemia, hyperbilirubinemia and polycythemia were higher than those of the control group, no statistical difference was noted. Conclusions GIGT may have adverse effects on the newborns