年龄相关椎体骨赘发生率及其分布的参考值(英文)

Database of incidence and distribution of age-related vertebral osteophyma

背景:在工伤等所引起的腰椎间盘病变的鉴定中,由于缺乏年龄相关的椎体骨赘发生率及其分布的参考值而很难对其做出正确的评判。目的:建立年龄相关的椎体骨赘发生率及其分布的参考值数据库。设计:相互对照的回顾性研究。地点和对象:由华中科技大学同济医学院协和医院骨科和德国海德堡大学骨科医院完成,研究对象:选用德国海德堡大学骨科医院资料库中1980/1999腰椎侧位X线片1240张,男性X线片633张,平均年龄20～87岁;女性607张,平均年龄20～92岁。干预:测量腰椎侧位X片1240张,将T12～L5椎体骨赘分为椎体上缘刺状骨赘及椎体下缘刺状骨赘,均以“有”或“无”记录,男、女两组分别按每10岁一个年龄段分为Ⅰ,Ⅱ,Ⅲ,Ⅳ,Ⅴ,Ⅵ组计算骨赘发生率,进行统计学分析。主要观察指标:年龄、性别对骨赘发生率的影响及骨赘分布。结果:椎体骨赘发生率随年龄的增长而增加,Ⅴ组分别为48.5%和33.7%,男性发生率明显高于女性发生率(χ2=4.38,P<0.05);男性骨赘最好发于第4腰椎,女性骨赘最好发于第3腰椎。结论:应用年龄相关的椎体骨赘发生率及其分布的参考值数据库,通过对比分析,可对椎体骨赘的发生情况做出客观评价。

BACKGROUND:It is very difficult to make accurate judgment in the evaluation of the pathological changes in lumbar intervertebral discs caused by industrial ac cidents because of lacking of the incidence of age-related vertebral osteophyma and its distribution database.OBJECTIVE:To establish a database on the incidence and distribution of age-re lated vertebral osteophyma.DESIGN:An inter-control retrospective study was conducted.SETTING and PARTICIPANTS:The study was completed in the Department of Orthopae dics of Union Hospital,Tongji Medical College of Huazhong University of Science and Technology and Orthopeadic Hospital of Heidelberg University,Germany.Subject s: 1240 pieces of X-ray of lumbar vertebra lateral position from database of He idelberg University,Germany from 1980 to 1999 were selected with 633 pieces of m ale X-rays aged from 20 to 87 years old and 607 pieces of female X-rays aged f rom 20 to 92 years old.INTERVENTIONS:Totally 1240 pieces of X-ray were examined.T12-L5 vertebral os teophyma were divided into vertebral superior border thorn osteophyma and verteb ral inferior border thorn osteophyma and recorded with 'yes' or 'no'.Males and females were grouped into 6 groups(I,Ⅱ,Ⅲ,Ⅳ,Ⅴ and Ⅵ) separately accordi ng to their age group, every 10 years old was set in an age group.The incidence of osteophyma was calculated for statistical analysis.MAIN OUTCOME MEASURES:The effects of age and gender on the incidence of osteop hyma as well as its distribution.RESULTS:The incidence of osteophyma increased along with the increase of the a ge.The incidences in male and female of V group were 48.5% and 33.7% respect ively, in which the incidence in male was significantly higher than female(χ2=4 .38, P< 0.05).The most susceptible position was L4 in males and L3 in females.CONCLUSION:It can objectively evaluate the incidence of vertebral osteophyma t hrough comparative analysis by applying the database of incidence and distributi on of age-related vertebral osteophyma.