羟基喜树碱联合免疫增强剂治疗癌性腹水

Treatment of cancerous ascites with hydroxycamptothecin combined with immune preparation

目的 评价羟基喜树碱 (HCPT )联合免疫增强剂治疗癌性腹水的临床疗效。方法 将 78例癌性腹水病人分组行羟基喜树碱或羟基喜树碱联合免疫增强剂的腹腔化疗 ,并行空白对照 ,对其化疗后的腹水量及癌细胞数进行统计分析。结果 羟基喜树碱或羟基喜树碱联合免疫增强剂两组的腹水量与癌细胞数与对照组对比有显著差异。

Objective To evlauate the cli ni cal effect of hydroxycamptothecin(HCPT) combined with immune preparation on canc erous ascites.Methods Seventy eight patients with cancerous as citic fluid were divided into three groups.Group A were treated with HCPT,group B were treated with HCPT and immunocytokines,group C was control.The cancer cell and the volume of ascites in each group were analyzed.Results The number of cancer cells and the volume of ascites in group A and group B were lower than those in group C.The statistical difference was significant. Conclusion Combined HCPT and immunocytokines is an effective way to can cerous ascitic fluid.