前列腺增生症致尿路梗阻对膀胱癌复发的影响

Effects of ureteric obstruction induced by benign prostatic hyperplasia to recurrence of bladder cancer

目的 :探讨前列腺增生症 (BPH)致尿路梗阻对膀胱癌 (BTCC)复发的影响。方法 :回顾性分析 37例BTCC并发BPH患者的临床资料 ,其中 2 2例行膀胱部分切除术 (A组 ) ,15例行膀胱部分切除术和前列腺切除术或膀胱造瘘术 (B组 )。结果 :随访 12～ 2 4个月 ,A、B两组复发率分别为 36 .4 %、2 0 .0 % ,两组比较差异有显著性意义 (P <0 .0 1) ;两组平均复发时间比较差异无显著性意义 (P >0 .0 5 )。结论 :BPH致尿路梗阻是BTCC复发的重要因素 ,对BTCC并发BPH致尿路梗阻者 。

Purpose:To study the effects of ureteric obstruction induced by BPH to recurrence of bladder cancer.Methods:The clinical data of 37 cases of patients with bladder transitional cell carcinoma and BPH were retrospectively reviewed. Among the 37 patients, 22 had undergone partial cystectomy along(A group) and the rest of 15 had undergone partial cystectomy and suprapubic transvesical prostatectomy or and suprapubic cystectomy(B group) at the same time.Results:The follow-up period ranged from 12～24 months. Recurrence rate of A and B groups is 36.4% and 20.0% respectively, significant differences were observed in two groups (P< 0.01), and there were no significant differences in mean interval of recurrence(P> 0.05).Conclusions:Ureteric obstruction induced by BPH is an important factor to the recurrence of bladder transitional cell carcinoma. To the patients of bladder cancer with BPH, relief of ureteric obstruction would decrese recurrence rate of bladder cancer.