肿瘤患者情感障碍及相关因素调查分析

Investigation of Mood Disorder and Its Related Factors in Patients with Cancer

[目的]了解住院肿瘤患者抑郁、焦虑情绪的发生率,并对其相关因素进行分析。[方法]对540例肿瘤住院患者,应用抑郁自评量表(SDS)、焦虑自评量表(SAS)、汉密顿抑郁量表(HAMD)、汉密顿焦虑量表(HAMA)和自行设计的情感障碍影响因素调查表,进行情感状况及其相关因素的调查和分析。[结果]肿瘤患者抑郁和焦虑的发生率分别为51.1%和20.2%;患者的SDS、SAS标准分(50.15±11.62,42.42±9.43)显著高于常模(P<0.01);化疗组患者情感障碍阳性率均显著高于手术组和放疗组(P<0.01)。与早期及中期相比,晚期肿瘤患者的情感障碍阳性率显著增高(P<0.01)。影响肿瘤患者的情感因素诸多,但以对医疗费用、治疗效果的担心(71.1%,61.9%)最为显著。[结论]接受化疗及晚期的肿瘤患者具有更多的情绪障碍,应及早给予心理干预和必要的社会支持,以提高患者的治疗效果及生存质量。

To investigate the incidence of depression and anxiety, and related factors in patients with cancer.Five hundreds and forty in-patients with cancer were tested with Self-Rating Depression Scale (SDS), Self-Rating Anxiety Scale (SDS), Hamilton Depression Scale (HAMD), Hamilton Anxiety Scale (HAMA) and self-devised questionary of mood disorder factors.The incidence of depression and anxiety(51.1%,20.2%)in in-patients with cancer was significantly higher than that in the control.The standard score of SDS and SAS in patients (50.15±11.62,42.42±9.43) were significantly higher than those in control(P<0.01).The prevalence of mood disorder was higher in the patients with chemotherapy than that in those with surgery or radiotherapy(P<0.01).The prevalence of mood disorder was higher in the patients with advanced stage than that in those with early stage(P<0.01).Many factors influenced the mood status of in-patients with cancer,especially for medical expense and therapeutic effect(71.1%,61.9%).[Conclusions]The in-patients of advanced cancer with chemotherapy exist more mood disorder.Early psychological intervention and some social support should be offered for cancer patients with advanced stage or with chemotherapy to increase their therapeutic effect and quality of life.