支气管动脉碘油化疗栓塞术对非小细胞肺癌患者生活质量的影响

The Impact of Bronchial Arterial Lipiodol Chemoembolization on the Quality of Life for Patients with Non-small Cell Lung Cancer

[目的]探讨支气管动脉碘油化疗栓塞术对非小细胞肺癌患者近期生活质量的影响。[方法]采用肺癌治疗功能评价量表FACT鄄L中文版对33例使用超选择支气管动脉碘油化疗栓塞术治疗的非小细胞肺癌患者的近期生活质量进行测定,分析介入术前、术后1个月及3个月患者生活质量的变化,并与同期采用全身化疗的30例非小细胞肺癌患者进行比较。[结果]化疗栓塞组术后1、3个月的生活质量评分均较术前明显提高(P<0.01)。与全身化疗比较,化疗栓塞组在临床疗效和提高患者术后生活质量程度方面优于全身化疗组(P<0.05)。与疾病症状和治疗副作用有关的项目评分(分别为生理状况和附加关注)显示,化疗栓塞组在分项评分中同样优于全身化疗组(P<0.05)。[结论]超选择支气管动脉碘油化疗栓塞术比全身化疗更能提高中晚期非小细胞肺癌患者的生活质量。

To evaluate the short-term quality of life(QOL) for patients with non-small cell lung cancer(NSCLC) undergoing superselective bronchial arterial Lipiodol chemoembolization.The Chinese version of the Functional Assessment of Cancer Therapy-Lung(FACT-L)scales was used to evaluate the QOL in 33 cases with NSCLC undergoing superselective bronchial arterial Lipidol chemoembolization.The QOL was evaluated before chemoembolization and 1 month,3 months after,and compared with 30 cases undergoing systematic chemotherapy.In the chemoembolization group,the score of QOL at 1 month and 3 months postoperation were higher than that at preoperation(P<0.01).The score of QOL in the chemoembolization group was higher than that in the systematic chemotherapy group(P<0.05).The scores from the physical well-being factor and the additional concerns of FACT-L scales,were significantly different between the chemoembolization group and the systemic chemotherapy group(P<0.05).[Conclusion]The treatment of superselective bronchial arterial Lipidol chemoembolization for NSCLC is better than systemic chemotherapy on the improvement of QOL.