从生物有机化学到化学生物学

From Bioorganic Chemistry to Chemical Biology

生物体系中的发现一直是与小分子连系在一起的。生物有机化学是生物学和有机化学相互交叉发展起来的新领域 ,特别是小分子与蛋白结合后引起蛋白功能变化的研究如抑制作用和活化。化学生物学和结构多样性有机合成使系统研究生物学成为可能 ,人工转录因子可以用作探针来发现生命过程中新的奥秘。

Small molecules have long been associated with biological discoveries. Bioorganic chemistry is a new discipline emerging from the interaction of biology and organic chemistry especially in the field to study the binding of a small molecule to the protein that results in a perturbation of function, either inhibition or activation. Chemical biology and diversity-oriented organic synthesis make possible the systematic exploration of biology and artificial transcription factors be used as a probe for the discovery of new insights into life processes.