烧伤后血与血钙浓度变化与补钙疗效分析

Change of blood calcium level post burn and the efficacy of calcium therapy

目的 :寻找烧伤后血钙降低的规律与最佳补钙时机。方法 :取烧伤后 2 0天内的未补钙组与补钙一组和补钙二组各 30例 ,进行组间对照。观察各组血钙及其它离子的变化。结果 :三组血钙浓度均低于正常值 (2 2 5mmol/L～2 75mmol/L) ,但以未补钙组烧伤后血钙降低明显 ,第三天达最低值 ,持续时间与烧伤严重程度成正比 ,一般在伤后三周趋向恢复 :补钙一组 (连续 5天补钙 )血钙变化最小 ,补钙二组 (隔日补钙 10天 )次之。结论 :烧伤早期补钙可维持血钙浓度 ,早期连续补钙 5天较隔日补钙

Objective: To study the change of blood calcium level post burn and the best time of calcium therapy. Method: Burn patients were divided into 3 groups, 30 patients in each group. In calcium therapy group one, patients were injected with 10 ml 10% calcium gluconate solution 2 times every day for 5 days successively. In calcium therapy group two, patients received calcium gluconate injection every other day for 10 days and in control group, no calcium gluconate was applied. Blood concentration of calcium and other ions were determined and the results compared. Result: Patients in the 3 groups had blood calcium concentration lower than normal value (2.25～2.75 mmol/L). Patients in the group without calcium therapy had their blood calcium level lowered most significantly and reached the lowest value at day 3. The duration of low blood calcium concentration was positively related to the severity of burn and gradually recovered after 3 weeks. Blood calcium concentration drop of patients in calcium therapy group one was less than that of patients in calcium therapy group two. Conclusion: Early calcium therapy can help maintain blood calcium level. Every day injection of calcium gluconate for 5 days is more efficacious than every other day for 10 days.