菲立磁增强MRI对肝脏局灶性病变的诊断价值

Diagnostic Value of Feridex-enhanced MRI forFocal Hepatic Lesions

目的:探讨菲立磁增强MRI检查在肝脏局灶性病变诊断中的应用价值。方法:对34例临床怀疑有肝脏占位性病变,行常规MR或CT检查诊断困难的患者行菲立磁增强MR检查。用定量的方法研究增强前后T1WI及T2WI图像上病灶信号强度的变化,采用配对t检验分析其变化的显著性。结果:增强后肝脏实质T2WI信号明显降低,良、恶性病变的信号变化不同。病变的检出量增加,显示更清楚。结论:菲立磁增强MR检查可明显提高肝脏局灶性病变的检出率及鉴别诊断的准确性。

Objective: To evaluate the applicable value of Feridex-enhanced MRI in the diagnosis of focal hepatic lesions. Methods: Feridex-enhanced MRI was performed in 34 patients with suspected focal hepatic lesions, in which conventional CT or MR had difficulties in diagnosing. Study the changes in signal intensity of the lesions before and after Feridex enhancement on T1WI and T2WI images with quantitative method. Analyse the significance of the changes with paired t-test. Results: After the injection of Feridex, the signal intensity of hepatic parenchyma reduced significantly on T2WI, while the changes of the signal intensity of benign and malignant lesions were different. On enhanced T2WI, more lesions were detected and the lesions displayed more clearly. Conclusion: Feridex-enhanced MRI can improve the detection of focal hepatic lesions and is very helpful in differential diagnosis.