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二硫化碳对女工生殖结局影响的研究 被引量:31

Studies on the Effects of Carbon Disulphide on the Outcome of Pregnancy of Female Workers
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摘要 以河北、河南、辽宁、湖北四个化纤厂接触CS_2的已婚女工682人为观察对象,以同地区棉纺厂已婚女工745人为对照组,应用历史性前瞻的方法,进行了生育史的调查。接触组妊娠次数1112次,对照组为1494次。结果,子代出生缺陷发生率接触组为26.44‰,显著高于对照组(13.07‰),RR2.02,95%可信限1.13~3.60,P<0.025。在调正了被动吸烟及胎次等可能的混杂因素后,经Mentcl-Haenszel 法检验,两组间仍有显著差异,X^2-MH 5,865,P<0.05;OR-MH 2.058,95%可信限1.148~3.692,SRR 2.139。但未见有特异畸形出现。 The population studied was composed of 682 married female workers ex-posed to CS_2 in four viscose rayon factories located in He Bei,He Nan,Liao Ning and Hu Bei provinces with 745 married female textile workers fromthe same localities as controls.The pregnancy and child bearing histories wereinvestigated by retrospective cohort study.There were 1112 times pregnanciesin the exposed group and 1494 times in control group.Results showed that theincidence of birth defect in children of female workers exposed to CS_2 was26.44‰,significantly higher than that of the control(13.07‰),RR2.02,and 95%CI was 1.13-3.60,P<0.025.After adjusting with pregnancy orderand passive smoking by Mentle-Haenszel method,the X^2-MH was 5.865,P<0.05,OR-MH 2.058,95% CI 1.148-3.692,SRR was 2.139.However,no specific type of malformations were found.
出处 《中华劳动卫生职业病杂志》 CAS CSCD 1992年第1期1-5,共5页 Chinese Journal of Industrial Hygiene and Occupational Diseases
关键词 二硫化碳 生殖 女工 Carbon Disulphide Birth Defect Outcome of Pregnancy
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  • 1盛叶舟,王簃兰.职业铅接触对女工及其子代的影响[J]工业卫生与职业病,1987(01).
  • 2龚梓初.三硝基甲苯的慢性影响及远期效应[J]铁道劳动卫生通讯,1986(04).
  • 3任淑明.接触化学物质有胚胎损失的十八对夫妇染色体畸变分析[J]中华劳动卫生职业病杂志,1986(06).
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