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内源性阿片肽参与痛信息调控的机制 被引量：14

The mechanisms of endogenous opioid peptides participate in the modulation of pain information
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作者 李辉 李云庆
机构地区 第四军医大学解剖学教研室
出处 《神经解剖学杂志》 CAS CSCD 北大核心 2004年第2期191-196,共6页 Chinese Journal of Neuroanatomy
基金 国家重点基础研究计划"脑基础及脑重大疾病的基础研究"(No.G19990 5 40 0 4) 国家自然科学基金(No. 3 9970 2 3 9)资助项目
关键词 内源性阿片肽 痛信息调控 机制 哺乳动物 分类 阿片受体
分类号 R33 [医药卫生—人体生理学]
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参考文献48

  • 1Millan MJ. Descending control of pain. Prog Neurobiol,2002;66:355-474
  • 2Willis WD, Westlund KN, Carlton SM. Pain. In: Paxions G ed. The rat nervous system, 2nd ed. San Diego: Academic Press, 1995,725-750
  • 3Li YQ, Li H, Kaneko T et al. Substantia gelatinosa neurons in the medullary dorsal horn: An intracellular labeling study in the rat. JComp Neurol, 1999;411:399-412
  • 4Yoshimura M, Nishi S. Excitatory amino acid receptors involved in primary afferent-evoked polysynaptic EPSPs of substantia gelatinosa neurons in the adult rat spinal cord slice.Neurosci Lett, 1992;143:131-134
  • 5Yoshimura M, Nishi S. Primary afferent-evoked glycine- and GABA-mediated IPSPs in substantia gelatinosa neurons in the rat spinal cord in vitro. J Physiol (London), 1995;482:29-38
  • 6Luo C, Kumamoto E, Furue H et al. Nociceptin inhibits excitatory but not inhibitory transmission to substantia gelatinosa neurones of adult rat spinal cord. Neuroscience, 2002;109:349-358
  • 7Wu SY, Dun SL, Wright MT et al. Endomorphin-like immunoreactivity in the rat dorsal horn and inhibition of substantia gelatinosa neurons in vitro. Neuroscience, 1999;89:317-321
  • 8Hori Y, Endo K, Takahashi T. Presynaptic inhibitory action of enkephalin on excitatory transmission in superficial dorsal horn of rat spinal cord. J Physiol, 1992;450:673-685
  • 9Kohno T, Kumamoto E, Higashi H et al. Actions of opioids on excitatory and inhibitory transmission in substantia gelatinosa of adult rat spinal cord. J Physiol, 1999;518:803-813
  • 10Glaum SR, Miller RJ, Hammond DL. Inhibitory actions of delta 1-, delta 2-, and mu-opioid receptor agonists on excitatory transmission in lamina Ⅱ neurons of adult rat spinal cord. JNeurosci, 1994;14:4965-4971

二级参考文献42

  • 1韩济生 罗非.阿片受体与阿片样物质[A].韩济生主编.神经科学原理[C].北京:北京医科大学出版社,1999.615～636.
  • 2Inoue M, Ueda H, et al. Protein kinase C-mediated acute tolerance to peripheral mu-opioid analgesia in the bradykinin nociception test in mice. J Pharmacol Exp Ther, 2000,293:662～669.
  • 3Ueda H, Yamaguchi T, Tokyama S, et al. Partial loss of tolerance liability to morphine analgesia in mice lacking the nociceptin receptor gene. Neurosci Lett, 1997,237:136～138.
  • 4Ueda H, Inoue M. Peripheral morphine analgesia resistant to tolerance in chronic morphine treated mice. Neurosci Lett, 1999,266:105～108.
  • 5Stein C, Comisel K, Haimerl E. Analgesic effect of intraarticular morphine after arthroscopic knee surgery. N Engl J Med, 1991, 325:1123～1126.
  • 6Likar R, Schafer M, Paulak F, et al. Intraarticular morphine analgesia in chronic pain patients with osteoarthritis. Anesth Analg, 1997,84:1313～1317.
  • 7Stein C, Hassan AHS, Lehrberger K, et al. Local analgesic effect of endogenous opioid peptides. Lancet, 1993,342:321～324.
  • 8Kolesnikov YA, Jain S, Wilson R, et al. Peripheral morphine analgesia: synergy with central sites and a target of morphine tolerance. J Pharmacol Exp Ther,1996,279:502～506.
  • 9Stein C. Peripheral mechanisms of opioid analgesia. Anesth Analg, 1993,76:182～191.
  • 10Buerkle H, Boschin M, Marcus MA, et al. Central and peripheral analgesia mediated by the acetylcholinesterase inhibitor neostigmine in the rat infoamed knee joint model. Anesth Analg, 1998,86:1027～1032.

共引文献33

同被引文献191

引证文献14

二级引证文献162

神经解剖学杂志
2004年 第2期

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