摘要
目的 :研究 2型糖尿病患者炎症因子C反应蛋白 (CRP)、肿瘤坏死因子α(TNF α)、IL 6浓度及外周血白细胞水平变化。方法 :选择健康成人 30例 ,高血压病人 30例 ,2型糖尿病病人 4 5例 ,测定各组人群超敏C反应蛋白 (Hs CRP)、TNF α、IL 6、白细胞 (WBC)水平 ,观察炎症介质在各组人群中的差异。结果 :高血压组和 2型糖尿病组的血清炎症介质水平较基础值均有升高 ,而糖尿病组血清炎症介质水平上升更明显 ,与另两组差异有显著性。结论 :2型糖尿病病人存在高水平炎症介质 ,即有炎症反应存在。
Objective:To investigate the changes in concentration of serum inflammation media (CRP?TNF-α?IL-6) and peripheral WBC counter in type 2 diabetes .Methods:Selected 30 normal individuals,30 hypertension individuals and 45 type 2 diabetics to test their hs-CRP? TNF-α?IL-6 and WBC.Result:Inflammation media of hypertension group were higher than controls(CRP? TNF-α,P<0.05), and in type 2 diabetics they were significantly higher than hypertension individuals(P<0.01).Conclusion:Type 2 diabetics had higher level inflammation media.
出处
《江苏大学学报(医学版)》
CAS
2004年第2期139-141,共3页
Journal of Jiangsu University:Medicine Edition
关键词
2型糖尿病
炎症介质
Type 2 diabetes
Inflammation media