立体定向适形放射治疗危重肝脏肿瘤12例报告

Stereotactic conformal radiotherapy for hepatic tumors

目的 本组报告立体定向适形放射治疗肝脏肿瘤 12例 ,并作临床分析。方法 自 1997年 5月 -2 0 0 1年 10月治疗 12例肝脏肿瘤。肿瘤的临床靶体积 (CTGV)为 0 .6-2 3 2cm3 (平均为 40 .6cm3 )。计划靶体积处方计量是 3 .96-7.0 0Gy(平均为 5 .14Gy)。分 5 -8次照射。结果 治疗过程中无一例死亡。患者一般状况评分 (KPS)评发 ) :治疗前为 2 0 -90分 ( 5 4± 2 5 .9分 ) ,治疗后 3 0 -10 0分( 74± 2 3 .9分 )。随访 1-4年期间 ,按实体瘤标准 :完全缓解 (CR) 3例 ;部分缓解 (PR) 5例 ;无变化(NC) 3例 ;进展 (PD) 1例。肿瘤控制有效率为 91.6%。

Objective To analyze the effects of stereotactic conformal radiotherapy for hepatic tumors. Methods 12 patients with hepatis tumors underwent stereotactic conformal radiotherapy from May of 1997 to Oct. 2001. The clinical target volume (CTV) of tumors ranged from 0.6 to 232 cm 3 with a mean of 40.6 cm 3. The irradiation dose to the planning target volume (PTV) was 3.96-7.00 Gy (mean 5.14 Gy), which was applied within 5-8 times (the prescribed does PD). Results No patient died during treatment. KPS score ranged from 20 to 94 (54±25.9) before treatment, and from 30 to 100 (74±23.9) after treatment. During the period of follow-up (1-4 years), tumor was completely remittent in 3 cases, partly remittent in 5 cases, no changed in 3 cases, and deteriorated in 1 cases, the effective rate was 91.6% Conclusions Stereotactic conformal radiotherapy is effective in the treatment hepatic tumors.