脑血管病死亡与体重指数及胆固醇相关性的研究

STUDY ON THE CORRELATION BETWEEN THE MORTALITY OF CRD AND BMI OR SERUM CHOLESTEROL LEVEL

目的 :为了研究脑血管病 (CVD)死亡与体重指数 (BMI)及血清总胆固醇的关系。方法 :我们于 1987年在长春市选择有代表性的社区 ,35岁以上无CVD病史的 2 72 3人做队列人群 ,进行各项CVD危险因素调查 ,12年后随访队列人群 ,进行全死因调查 ,并行统计分析。结果 :低体重者全死因死亡率显著高于正常体重及超重者 ,但未发现BMI与CVD死亡的确切关系。高胆固醇与缺血性CVD死亡有关低胆固醇与出血性CVD关系密切。结论 :超重或低体重均对健康有利 ;对高胆固醇的脑梗塞患者应以降血脂冶疗为主 ,而低胆固醇的出血病人应以调整血脂水平至正常范围为主。

Objective :In order to investigate the relation ship between the mortality of CVD with BMI and serum cholesterol level. we selected some typical commrnctiesin Chang Chun since 1987,2723 subjects who were over 35 years with no CVD history are involved in this strdy .Methods: we investigated every dargerous factors of CVD. Twelve years later,we followed the cohort and studied the all-causes mortality.Results:subjects with under weight had significantly higher all-causes mortality than those with normal weight and overweight. but we didn't find any definite relationships between BMI and the death of CVD. high serum cholesterol level. is concerned with the death of ischemic CVD. while low serum cholesterol level ins concerned with the death of hemorrhagic CVD. Conclusions:over weight or under weight are harmful to health, in order to lower the mortality of CVD, the main therapy to the patients who are suffered from ischemic CVD with high seum cholesterol level is to lower their serum cholesterol ,however to adjust the serum cholesterol level is most important to those hemorrhagic CVD patients.