血脂康对老年高血脂血症患者血管内皮功能的影响

Effect of Xuezhikang on endothelial function in aged patients with hyperlipidemia

目的 观察血脂康对老年高脂血症患者血管内皮功能的影响。方法 6 5例老年高脂血症患者随机分为治疗组(血脂康 ) 35例 ,对照组 (普拉固组 ) 30例 ,治疗组予服血脂康胶囊 0 6 ,2次 /天 ,对照组予服普拉固片 10mg ,1次 /晚 ,连用 8周 ,治疗前后测定两组TG、TC、HLD -C及ET水平。结果 两组治疗前TG、TC、HLD -C及ET水平相似 (P >0 0 5 ) ,治疗后血脂康与普拉固一样具有降低高脂血症患者的TG、TC、HLD -C、ET水平并升高HLD -C ,与治疗前比较差异显著 (P <0 0 5 )。结论 血脂康可以降低老年高脂血症患者的血脂异常 ,并明显改善患者的血管内皮功能。

Objective To study the effect of Xuezhikang(XZK) on endothelial function in aged patients with hyperlipidemia.Methods 66 cases aged patients with hyperlipidemia were randomly allocated to receive XZK(n=35) 0.6 Bid in treated group and pravachol(n=30) 10mg QN in control group for 8 weeks,TG、TC、LDL-C、HLD-C and ET were determined before and after treatment.Results TG、TC、LDL-C and ET levels were similar before treatment in both groups(P>0.05).After treatment TG、TC、LDL-C and ET decreased and HLD-C increased in both groups(P<0.05).Conclusion XZK could markedly adjust the abnormal blood lipids and improve the endothelial function in aged patients with hyperlipidemia.