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病毒性肝炎发病机制中环氧合酶的作用 被引量：1

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摘要 0 引言。肝细胞癌(HCC)是世界上最常见的恶性肿瘤之一，常是慢性肝炎和肝纤维化的终末并发症．对于HCC的治疗仅是姑息性的，长期存活很少．肝内转移是肿瘤切除后复发和预后差的主要原因．慢性HBV、HCV感染常发展成肝硬化、HCC．环氧化酶(cyclooxygenase，COX)在维持组织内环境稳定，促进细胞生长，抑制凋亡等多种生命活动中发挥重要作用．近年研究表明，COX在慢性乙型肝炎(HBV)、丙型肝炎(HCV)感染发展成肝硬化、HCC及肿瘤转移的发生中有重要作用．
作者 刘敏 成军 张树林
机构地区 中国人民解放军第 西安交通大学第一医院传染科
出处 《世界华人消化杂志》 CAS 2004年第2期417-419,共3页 World Chinese Journal of Digestology
基金 国家自然科学基金项目 No.C39970674 No.C03011402 No.C39900130 No.C30070689军队"九 五"科技攻关项目 No.98D063军队回国留学人员启动基金项目 No.98H038军队"十 五"科技攻关青年基金项目No.01Q138军队"十 五"科技攻关面上项目 No.01MB135
关键词 病毒性肝炎 发病机制 肝细胞癌 HCC 环氧合酶 肿瘤
分类号 R512.62 [医药卫生—内科学]
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参考文献25

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同被引文献14

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世界华人消化杂志
2004年 第2期

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