复方托吡卡胺滴眼时间间隔对青少年验光和散瞳的影响

Influence of time interval between instillation of tropicamideo phenylephrine ophthalmic solution on refraction and mydriasis in adolescent

目的 研究 2次滴眼时间间隔对青少年验光和散瞳效果的影响。方法 在本院 2 0 0 1～ 2 0 0 2年门诊散瞳验光的青少年屈光不正患者中 ,随机抽取 73例 14 6眼 ,年龄 8～ 2 5岁 ,平均 14 4岁 ,滴 2次复方托吡卡胺之间间隔 1min或5min ,然后进行检影并记录瞳孔直径 ,1周后重复此过程 ,改变时间间隔。结果 滴 2次眼液的时间间隔对检影结果无显著性差异 (P >0 0 5 ) ,对散瞳效果也无显著性差异 (P >0 0 5 )。结论 间隔 1min滴

Objective To investigate the influence of the time interval between the instillation of the two drops on refraction and mydriasis in adolescent.Methods We conducted a crossover study on 73(146 eyes) adolescents aged 8～25 years tropicamideo phenylephrine ophthalmic solution was instilled at one minute or five minutes time interval.Retinoscopy was performed and the mydriatic effect was recorded.One week later,the procedure was repeated,this time with a different time interval.Results The time interval between the instillation of the two drops had no significant influence on retinoscopy results( P >0 05,respectively).Conclusion Instilling two drops of tropicamideo phenylephrine ophthalmic solution one minute apart is as effective as instilling them five minutes apart.