肝病患者血清TBA、PA和SIL-2R的意义

The Clinical Significance of Determining TBA、PA and sLT-2R Contents in Patients with Hepatopathy

目的 :探讨血清总胆汁酸 (TBA)、前白蛋白 (PA )和可溶性白介素 2受体 (SIL - 2 R)含量测定对肝病的诊断意义。方法 :TBA、PA用杜邦 RXL 全自动生化分析仪检测 ,SIL- 2 R用双抗体夹心 EL ISA法检测。结果 :急性肝炎、慢性肝炎、肝硬化和肝癌患者的血清 TBA和 SIL - 2 R水平升高 ,PA水平下降 ,各疾病组与对照组比较 ,差异均有显著。结论 :检测肝脏疾病患者血清 TBA、PA和 SIL - 2 R可了解患者肝细胞损伤程度 ,判断患者细胞免疫力功能状态 ,为患者的免疫治疗提供理论依据 ,并对患者的病情监视、疗效观察及判断预后都有一定实用价值。

Objective To study the changes of TBA、PA and sIL-2R in patients with Hepatopathy.Methods TBA and PA were detected by du pont RXL automatic biochemistry analyzer,sIL-2R was detected with ELISA.Results TBA and PA were sighnificant high in patients with acute hepatitis,chronic hepatitis,cirrhosis of liver and hepatocarcinoma,and sIL-2R was sighnificant lower in patients with hepatopathy.Condusion TBA,PA and sIL-2R levels in serum is usuful in lbservating patient's condition,observing effectand judging prognosi of hepatopathy.