翼状胬肉切除联合羊膜移植术临床应用

Conjunctival reconstruction after excision of pterygium with human amniotic membrane

目的 :观察保存人羊膜移植术在翼状胬肉切除术后结膜重建及防止翼状胬肉复发中的临床疗效。方法 :对 3 6只眼翼状胬肉 (包括 4只眼复发性翼状胬肉 )行扇形切除 ,在角膜缘 1∶3 0～ 4∶3 0分离 ,鼻侧接近半月皱襞。尔后应用超低温 (-80℃ )冷冻保存的人羊膜进行修补。结果 :随访观察 5～ 16个月 ,平均 10个月 ,翼状胬肉治愈率为 10 0 %。角膜上皮 3天内修复 ,羊膜植片水肿在 7～ 10内消失 ,2～ 3周新生血管化完成。结论 :翼状胬肉切除联合羊膜移植术可有效地降低翼状胬肉的术后复发率。

Objective: To evaluate the curative effect of preserved human amniotic membrane transplantation for the conjunctival reconstruction and the prevention from recurrence after excision of pterygium. Methods: 36 eyes of pterygium,including 4 eyes of re-set pterygium were excised.The conjunctiva was excised between corneal limbus from 1∶30 to 4∶30 Hrs position and the site of near the plica semilunaris.Preserved human amniotic membrane was transplanted to cover the exposed sclera. Results: All the cases got satisfied curative effect (100%) during the follow up of 5～16 months (mean 10 months).Corneal epithelium recovered within 3 days after surgery,Amniotic membrane grafts edema disappeared within 10 days.The neovascularization in amniotic membrane graft were found 2～3 weeks after operation. Conclusions: Pterygium excision with preserved human amniotic membrane transplantation can significantly prevent the recurrence of pterygium.