提高胰腺癌的手术疗效关键在于根治切除

Radical resection plays a key role in the outcome of pancreatic cancer patient

目的 总结胰腺癌各种治疗方法的效果。方法 回顾分析本院1990年1月-2003年3月收治的545例胰腺癌病例的治疗经过,比较各种治疗方法的生存率。结果 本组手术385例,其中根治切除130例,姑息性切除34例,姑息性短路183例,单纯探查38例,单纯化疗26例,无特殊处理134例。根治切除组生存时间和其他各组的差异有显著意义,根治切除组1、3、5年生存率分别为61.19％、21.79％、10.63。结论 根治切除可提高胰腺癌病人的长期生存率。

Objective To summarize the outcome of different therapeutic methods for pancreatic cancer patient. Methods Clinical data of 545 pancreatic cancer cases treated in our department between January 1990 and March 2003 were analyzed retrospectively. The survival rates of various kinds of treatment methods were compared by Kaplan- Meier method. Results Of 545 patients, 130 underwent radical resection, 34 palliative resection, 183 palliative by- pass, 38 exploration operation, only 26 systemic chemotherapy, 134 received no special treatment. The survival rate in the radical resection group was significant higher than that in other 5 groups. The 1 - , 3 - , and 5 - year survival rates of the radical resection group was 61.19% , 21.79% , and 10.63% , respectively . Conclusions Radical resection can improve the long - term survival of pancreatic cancer patients but the palliative treatments have limited effect.