多电极射频消融治疗中晚期肝癌

Multielectrode radio frequency on advanced liver

目的 回顾性总结多极射频治疗肝癌疗效,研究治疗中晚期肝癌更好的方法。方法本组153例中晚期肝癌均施行多极射频治疗,直径>10cm的肿瘤行分次射频和局部注射化疗药物。治疗前评价肝功能,MRF治疗后维护肝功,防止肝衰。结果 显效104例,占68.6％;部分显效40例,占26.1％;无效9例,占5.8％;总有效率94.2％,无手术死亡。术后半年生存率94.8％,2例外生存超过2年。结论 多极射频治疗是一种安全性高、并发症少、疗效较好的主方法。

Objective The clinical outcome of advanced liver cancer which had been taken multielectrode radio frequency (MRF) ablation was summaried in this paper in order to explore a better therapeutic way for these patients. Methods MRF ablation was performed in 153 cases of patients with advanced liver cancer. In patients with big liver cancer (diameter> 10 cm) , MRF ablation was performed several times to cover the mass completely and local chemotherapy was also performed. The liver function was detected in every patient before and after MRF ablation therapy. After MRF therapy, liver function was maintained to prevent liver failure. Results With clinical evaluation, MRF was effective in 104 cases (68.6%) remarkably, 40 cases (26. 1%) partially, and 9 cases (5.8%) uselessly. The general effective rate was 94.2% . No surgical death was found in these patients. The 6 - month survival rate after MRF therapy was 94.8% and 2 cases survived more than 2 years. Conclusions MRF is a safe and effective in dealing with advanced liver cancer.