延缓毛发生长的动物实验

Experimental study on postpone the murine hair growth

目的:研究延缓毛发生长的方法。方法:将不同浓度EGF(Epidermal growth factor表皮生长因子)柔性脂质体及EGF普通脂质体分别涂抹于剃毛大鼠皮肤上,观察毛发生长速度。结果:局部外用高浓度EGF柔性脂质体的大鼠的毛发生长速度减慢,与对照组相比差异有非常显著性。结论:局部外用EGF柔性脂质体可能延缓大鼠毛发的生长。

Objective: To study the method of postponing the hair growth. Methods: 26 SD rats were given the local application of nano -liposome -bound EGF (333. 3μg/ml) . Compared with the same substance in lower concentration (166. 7μg/ml), or free form. Results: The growth of the Murine hair is postponed by the nano -liposome -bound EGF (333. 3μg/ml), the lower concentration and the free form is not. Conclusion: The local application of nano -liposome -bound EGF can postpone the growth of hair follicie.