MRI导向立体定向活检手术在颅内疑难病例诊断中的应用

MRI-guided stereotactic biopsy for questionable diseases in brain

目的 探讨MRI导向立体定向活检手术的准确性及其在颅内疑难病例诊断中的应用价值。 方法 安装CRW立体定向框架 ,采用MRI容积扫描与多层重建技术 ,对 2 6例临床表现不典型或CT扫描不能发现明确病灶的患者施行立体定向脑活检手术。 结果 2 6例患者均未出现因活检手术而造成的出血、偏瘫等严重并发症。所有患者均得到明确的病理诊断及相应的治疗。结论 MRI导向立体定向活检手术在准确性上明显优于CT导向活检手术 ;对于颅内疑难病例的诊断 ,也是一种有效的手段。

Objective To explore the accuracy and role of magnetic resonance imagine (MRI)-guided stereotactic biopsy for atypical diseases in brain. Methods Using MRI volume scan and multiplane reconstruction, MRI-guided stereotactic brain biopsies were performed with CRW stereotactia frame in twenty-six patients whose lesions were atypical or unable to be detected by CT scanning. Results No serious complication (intracranial hematoma,paralysis)caused by brain biopsy was found in all twenty-six patients. Definite pathologic diagnosis and appropriate treatment were given to these patients. The lesions included gliomatosis cerebri, brain cysticercosis and Krabbe′s disease, et al. Conclusions MRI-guided stereotactic brain biopsy is more accurate for pathological diagnosis than CT-guided stereotactic brain biopsy. MRI-guided stereotactic biopsy can provide reliable diagnosis and treatment especially for the questionable lesions in brain.