腮腺多形性低度恶性腺癌1例报道并文献复习

Polymorphous low-grade adenocarconoma of parotid: a case report with review of literature

目的 探讨多形性低度恶性腺癌 (小叶性或终末导管癌 )的临床病理特点、诊断及鉴别诊断。方法 通过光镜和免疫组化 ,对 1例腮腺多形性低度恶性腺癌进行病理组织学观察。结果 多形性低度恶性腺癌细胞形态较单一 ,但组织结构具有多样性。上皮膜抗原 (EMA)呈阳性。结论 这是一种不常见的肿瘤 ,多发于小涎腺 ,尤其是腭部 ,腮腺少见。尽管其具有浸润性生物学行为 ,但仍属于低度恶性肿瘤。彻底切除病变 ,可防止肿瘤复发。

Objective To study the clinical pathological characteristics of polymorphous low-grade adenocarinoma and its differential diagnosis. Methods A case of polymorphous low-grade adenocarinoma in parotid gland was studied by histopathological observation and immunohistochemical staining. Results The histopathological features of the tumor were the single cell form, but polymorphism of the tissue structures.Immunohistochemical staining showed EMA is positive. Conclusions The polymorphous low-grade adenocarinoma is an unusual tumor that has often occurred in the minor salivary gland, particularly of the palate, and rare in the parotid gland.though it has infiffradive biological behavior, it belongs to low-grade malignant tumour. Thorough removal of the tumor prevents its recurrence.