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骨形成蛋白与前列腺的关系 被引量:1

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摘要 骨形成蛋白 (BMP)是转化生长因子 β(TGFβ)超家族中最大的亚群。研究表明 ,BMP能够调控前列腺的发育和生长。前列腺和前列腺癌组织中有BMP及其受体的表达 ,提示BMP在前列腺行使正常生理功能、前列腺癌的发生和发展过程中发挥重要作用。此外 ,BMP特别是BMP6在前列腺癌中过表达 ,与前列腺癌的成骨性骨转移有密切关系。研究BMP与前列腺的关系 ,有助于了解前列腺的结构、功能及其物质基础 ,为研究前列腺疾病的发病机制、探索诊断和治疗途径提供基础和思路。
出处 《诊断病理学杂志》 CSCD 2003年第6期374-376,共3页 Chinese Journal of Diagnostic Pathology
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