摘要
目的 测定卵巢肿瘤患者血清IL 6 ,CA12 5水平 ,探讨其在卵巢肿瘤定性中的价值及其临床意义。方法 抽取 6 1例卵巢肿瘤患者血及 17例腹水患者腹水 ,采用ELISA法及胶乳凝集法测定IL 6 ,CA12 5。结果 IL 6对卵巢癌敏感性达 80 .9% ,特异性 77.3% .CA12 5对卵巢癌敏感性达 85 .7% ,特异性 80 .9% ,上述两项指标联合检测 ,敏感性达 95 .2 % ,特异性 73.9% .临床分期晚、组织分化低的卵巢癌患者血及腹水中IL 6 ,CA12 5水平明显升高。结论 IL 6 ,CA12 5为卵巢肿瘤定性诊断的良好指标 ,而且联合监测对卵巢肿瘤定性诊断更有意义。
Objective To determine the level of serum IL-6,CA 125 and explore the differential diagnostic value and clinical significance of the tumor markers in patients with ovarian tumor.Methods Using ELISA or Latex agglutination assay,serum and ascitic fluid IL-6,CA 125 61 cases of ovarian tumor are measured.Results Sensitivity and specificity of IL-6,CA 125 are 80.9%,77.3%,85.7%,80.9% respectively.Sensitivity and specificity of the combination of IL-6 and CA 125 are 95.2%,73.9%, respectively.The level of IL-6,CA 125 of serum and ascitic fluid in patients with advanced stage or lower histological differentiation are significantly higher than those in patients with early stage or higher histological differentiation.Conclusion IL-6,CA 125 are effective directors in the differential diagnosis of ovarian tumor,and combined assay of those parameters may be of great value in distinguishing ovarian benign tumor from malignant tumor. [
出处
《潍坊医学院学报》
2004年第1期34-36,共3页
Acta Academiae Medicinae Weifang
