双黄酮类化合物的合成研究——Ⅰ.芳香族1,4—二酮的合成

Study on the Synthesis of Some New Biflavonoids——Ⅰ.Synthesis of the aromatic 1,4—diketones

用丁二酰氯作为酰化试剂合成了五个芳香族1,4—二酮(3a—3e),产率较文献报道的有较大提高.同时用丁二酸酐作为酰化试剂也合成得到了3a.前法可用于制备1,4位含相同芳基的1,4—二酮,而后法则可用于1,4位含不同芳基的1,4—二酮的合成.

Five aromatic 1,4—diketones(3a—3e)were prepared by modifiedmethod using succinyl chloride as acylating reagent.The yield of the 1,4—diketones was much higher than the yield with the literature method.Aromatic 1,4—diketone(3a)was also prepared by using succinic anhydrideas acylating reagent.The first method could be used for the preparationof aromatic 1,4—diketones with the same aromatic groups,and the secondfor the different aromatic groups.