芬太尼和布比卡因用于外科术后自控镇痛

Fentanyl and Bupivacaine Used for Postoperative Patient-controlled Analgesia

目的 :比较芬太尼和布比卡因配伍以及哌替啶和异丙嗪配伍术后镇痛的效果。方法 :85例手术患者分成两组 ,Ⅰ组( 4 0例 )芬太尼 0 .2mg + 0 .12 5 %布比卡因 10 0ml利用微量泵进行术后自控镇痛 ,每小时 2ml,患者疼痛时可自行或由家属控制给药 1.5ml;Ⅱ组 ( 4 5例 )哌替啶 5 0mg和异丙嗪 2 5mg配伍im进行术后镇痛 ,疼痛时即肌注一次 ,下次用药时间一般不少于 6h。结果 :使用芬太尼和布比卡因配伍进行术后自控镇痛以及使用哌替啶和异丙嗪配伍肌注术后镇痛 ,两种方法镇痛效果无显著性差异 ,相比之下 ,前者具有操作简单、见效快、镇痛效果稳定。无成瘾性等优点。结论

Objective: To compare the efficency of analgesia between two groups of patients, the treated group was treated with fentanyl and bupivacaine by minimpump after operation, the controlled group was treate with pethidin and promethazine by muscle injection after operation.Methods: 85 patients were randomly divided into two groups: groupⅠ( n =40) (treated group) and group Ⅱ ( n =45)(controlled group). Result: The efficency of analgesia showed no significant difference between group I and group Ⅱ, but the former showed more convenience, rapid and stable effect, and no addiction.Conclusion: The analgesic method with fentanyl and bupivacaine after operation by minimpump was better than that with pethidini and promethazine by muscle injection after operation.